Good Cosmetic Ingredient NOAEL Data

Cadinene

INCI: CADINENE

CAS Number
29350-73-0
Function
Fragrance
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Safety

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Cadinene. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 156 mg/kg bw/day oral rat Subchronic COSMOS_DB

Expert Verdict

Cadinene is a fragrance ingredient permitted in cosmetics with established safety profile.

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Concern Level: Low

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Cadinene safe in cosmetics?

Cadinene is a fragrance ingredient permitted in cosmetics with established safety profile. The EU classifies Cadinene as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.

Is Cadinene allowed in the EU?

Cadinene EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cadinene do in cosmetics?

Cadinene functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 29350-73-0.

What is the Margin of Safety for Cadinene?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Cadinene?

The NOAEL (No Observed Adverse Effect Level) for Cadinene is 156 mg/kg bw/day based on a Subchronic study via oral route in rat. Source: COSMOS_DB.

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