Is Calcium Fructoborate safe in cosmetics?
Calcium Fructoborate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Calcium Fructoborate
Also known as: Borate(1-), bis[β-D-fructofuranosato(2-)-κO2,κO3]-, calcium (2:1), (T-4)-
INCI: CALCIUM FRUCTOBORATE
Calcium Fructoborate (CAS 250141-42-5) is a cosmetic cosmetic ingredient functioning as Skin conditioning — humectant. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 250141-42-5 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning — humectant
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
calcium bis((1S,1'S,5R,5'R,7R,7'R,8S,8'S)-5,5',7,7'-tetrakis(hydroxymethyl)-3,3'-spirobi[2,4,6-trioxa-3-boranuidabicyclo[3.3.0]octane]-8,8'-diol)
InChIKey
HRSMKOBEJUELDV-XBNRZDKMSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not CIR-reviewed; no FDA-specific restriction for cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Calcium Fructoborate.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Humectant
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Calcium Fructoborate.
Known Synonyms
Borate(1-), bis[β-D-fructofuranosato(2-)-κO2,κO3]-, calcium (2:1), (T-4)-
Chemical Function
Humectant
Softener and conditioner
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA count match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Adverse Event Associations
1
Frequently Asked Questions
Is Calcium Fructoborate allowed in the EU?
Calcium Fructoborate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Calcium Fructoborate do in cosmetics?
Calcium Fructoborate functions as: Skin conditioning — humectant. It is classified as a cosmetic ingredient in our database. CAS number: 250141-42-5.
Is Calcium Fructoborate used outside cosmetics?
Calcium Fructoborate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Calcium Fructoborate compliance across multiple jurisdictions:
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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