Regulatory Status
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Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
osure conditions? Based on the data provided, the SCCS considers hydroxyapatite (nano) safe when used at concentrations up to 29.5% in toothpaste, and up to 10% in mouthwash. This conclusion is based on the available evidence, which shows that hydroxyapatite (nano) does not pose a mut
osure conditions? Based on the data provided, the SCCS considers hydroxyapatite (nano) safe when used at concentrations up to 29.5% in toothpaste, and up to 10% in mouthwash. This conclusion is based on the available evidence, which shows that hydroxyapatite (nano) does not pose a mut
osure conditions? Based on the data provided, the SCCS considers hydroxyapatite (nano) safe when used at concentrations up to 29.5% in toothpaste, and up to 10% in mouthwash. This conclusion is based on the available evidence, which shows that hydroxyapatite (nano) does not pose a mut
posure conditions? Based on the data provided, the SCCS considers hydroxyapatite (nano) safe when used at concentrations up to 10% in toothpaste, and up to 0.465% in mouthwash. This safety evaluation only applies to the hydroxyapatite (nano) with the following characteristics: - compo
posure conditions? Based on the data provided, the SCCS considers hydroxyapatite (nano) safe when used at concentrations up to 10% in toothpaste, and up to 0.465% in mouthwash. This safety evaluation only applies to the hydroxyapatite (nano) with the following characteristics: - compo
Expert Verdict
Nano form is the primary concern with insufficient genotoxicity and absorption data for nano-HAP flagged by SCCS. Non-nano form is essentially bioidentical to bone mineral with very low hazard. Ensure particle size documentation in CPSR if used.
Frequently Asked Questions
Is Calcium Hydroxyapatite safe in cosmetics?
Nano form is the primary concern with insufficient genotoxicity and absorption data for nano-HAP flagged by SCCS. Non-nano form is essentially bioidentical to bone mineral with very low hazard. Ensure particle size documentation in CPSR if used. The EU classifies Calcium Hydroxyapatite as "permitted". Safety rating: GOOD. This ingredient has been reviewed by sccs.
Is Calcium Hydroxyapatite allowed in the EU?
Calcium Hydroxyapatite EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Calcium Hydroxyapatite do in cosmetics?
Calcium Hydroxyapatite functions as: Abrasive, bulking agent, oral care, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 1306-06-5.
What is the Margin of Safety for Calcium Hydroxyapatite?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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