Is Calcium Tartrate safe in cosmetics?
Calcium Tartrate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Calcium Tartrate
Also known as: 2,3-Dihydroxybutanedioic acid, calcium salt, Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, calcium salt (1:1), Tartaric acid, calcium salt
INCI: CALCIUM TARTRATE
Calcium Tartrate (CAS 3164-34-9) is a cosmetic cosmetic ingredient functioning as Skin conditioning, buffering agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 3164-34-9 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, buffering agent
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
calcium (2R,3R)-2,3-dihydroxybutanedioate
InChIKey
GUPPESBEIQALOS-ZVGUSBNCSA-L
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Adequate — No systemic toxicity concern at cosmetic use levels
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Calcium Tartrate.
Calculate MoS for your specific formulation with the MoS Calculator.
EPA ToxValDB — Toxicity Values
10 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).
| Endpoint | Value | Species | Route | Duration | Source |
|---|---|---|---|---|---|
| NOAEL | =3100 mg/kg-day | Rat | oral | chronic | EFSA |
| LD50 | >2000 mg/kg | Rat | oral | - | ECHA |
| LD50 | ~4109 mg/kg | Mouse | oral | - | ECHA |
| LD50 | =4109 mg/kg | Mouse | oral | - | ECHA |
| LD50 | =920 mg/kg | Rat | oral | - | ECHA |
| LD50 | >5000 mg/kg | Rat | oral | - | ECHA |
| LD50 | >5000 mg/kg | Rat | oral | - | ECHA |
| LD50 | ~920 mg/kg | Rat | oral | - | ECHA |
| LD50 | >=2000 mg/kg | Rat | oral | - | ECHA |
| LD50 | <=5000 mg/kg | Rat | oral | - | ECHA |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10,000 - 100,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Evaluation
CALCIUM L(+)-TARTRATE | 1983 | NO ADI ALLOCATED | TRS 696-JECFA 27/28 | NOT PREPARED
Source: WHO/JECFA
EU Food Improvement
Food additives
Source: EU Food Improvement Agents
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Calcium Tartrate.
Known Synonyms
2,3-Dihydroxybutanedioic acid, calcium salt
Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, calcium salt (1:1)
Tartaric acid, calcium salt
Chemical Function
Softener and conditioner
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Calcium tartrate
E Number
E354
ADI
30 mg/kg bw
Food Category
preservative
Frequently Asked Questions
Is Calcium Tartrate allowed in the EU?
Calcium Tartrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Calcium Tartrate do in cosmetics?
Calcium Tartrate functions as: Skin conditioning, buffering agent. It is classified as a cosmetic ingredient in our database. CAS number: 3164-34-9.
Is Calcium Tartrate used outside cosmetics?
Calcium Tartrate also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Calcium Tartrate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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