Is Calcium Thioglycolate safe in cosmetics?
Calcium Thioglycolate has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
Moderate
Cosmetic Ingredient
Calcium Thioglycolate
Also known as: EINECS 212-402-5, Mercaptoacetic acid calcium derivative, UNII-J96129652N
INCI: CALCIUM THIOGLYCOLATE
Calcium Thioglycolate (CAS 814-71-1) is a cosmetic cosmetic ingredient functioning as Depilatory agent, hair waving/straightening. EU Regulation 1223/2009 status: restricted, max 5.0%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 814-71-1 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Calcium Thioglycolate is classified GHS Danger (H301, H312, H315, H317, H319, H330, H335, H373) in the chemicals database but is restricted in EU cosmetics at max 5.0%.
Source: Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Depilatory agent, hair waving/straightening
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
calcium bis(2-sulfanylacetate)
InChIKey
CNYFJCCVJNARLE-UHFFFAOYSA-L
Regulatory Status
EU EU Status
restricted
EU Max Conc.
5.0%
US US Status
permitted
US Notes
Adequate only within Annex III limits; requires strict pH and concentration compliance
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Calcium Thioglycolate.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Abrasive
Depilatory
Pharmaceutical
Reducing agent
Expert Verdict
Expert safety assessment and concern-level summary for Calcium Thioglycolate.
Regulatory Flags
potential-allergen
Known Synonyms
EINECS 212-402-5
Mercaptoacetic acid calcium derivative
UNII-J96129652N
Chemical Function
Depilatory
Reducing agent
Pharmaceutical
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Calcium Thioglycolate allowed in the EU?
Calcium Thioglycolate EU regulatory status: restricted. Maximum allowed concentration: 5.0%. This is based on EU Regulation 1223/2009 and its amendments.
What does Calcium Thioglycolate do in cosmetics?
Calcium Thioglycolate functions as: Depilatory agent, hair waving/straightening. It is classified as a cosmetic ingredient in our database. CAS number: 814-71-1.
Is Calcium Thioglycolate used outside cosmetics?
Calcium Thioglycolate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Calcium Thioglycolate have different safety status in cosmetics vs industrial chemicals?
Calcium Thioglycolate is classified GHS Danger (H301, H312, H315, H317, H319, H330, H335, H373) in the chemicals database but is restricted in EU cosmetics at max 5.0%.
Compliance Tools
Check Calcium Thioglycolate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Acrylates/Vinyl Neodecanoate Crosspolymer
Excellent
Same category
Emulsion stabilising, film forming
Adipic Acid
Excellent
Same category
Buffering
Aluminum Magnesium Oxide
Excellent
Same category
Absorbent, bulking agent, opacifying ...
Ammonium VA/Acrylates Copolymer
Excellent
Same category
Antistatic, binding, film forming, ha...
Ammonium VA/Crotonic Acid Copolymer
Excellent
Same category
Antistatic, film forming, hair fixing...
Aphanothece Sacrum Polysaccharide
Excellent
Same category
Absorbent, emulsion stabilising, film...
(20S)-Protopanaxadiol
Moderate
Similar safety
(Cnidium Officinale/Coptis Chinensis/Glycyrrhiza Uralensis) Root Extract
Moderate
Similar safety
Skin conditioning
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
Moderate
Similar safety
Antimicrobial, antioxidant, humectant
(Eclipta Prostrata/Houttuynia Cordata) Leaf Extract
Moderate
Similar safety
Skin conditioning
(Lepidium Meyenii/Sarcodon Aspratus) Root Water
Moderate
Similar safety
Skin conditioning
(Licorice/Reynoutria Japonica) Root/Stem Extract
Moderate
Similar safety
Skin conditioning, antioxidant
Calcium Lactate
Excellent
Chemical family
Humectant, skin conditioning, bufferi...
CALCIUM ASCORBATE
Good
Browse nearby
Antioxidant, Skin Conditioning
CALCIUM BEHENATE
Good
Browse nearby
Anticaking, Opacifying, Viscosity Con...
Is Calcium Thioglycolate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Calcium Thioglycolate in your formulation.