Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Captan. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOEL | 300 mg/kg bw/day | oral | dog | oral | REACH |
| NOEL | 110 mg/kg bw/day | dermal | code:3484 | dermal | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
Expert Verdict
Fungicide with significant toxicity and CMR concerns; prohibited in all cosmetic formulations.
Regulatory Flags
Frequently Asked Questions
Is Captan safe in cosmetics?
Fungicide with significant toxicity and CMR concerns; prohibited in all cosmetic formulations. The EU classifies Captan as "prohibited". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by cir.
Is Captan allowed in the EU?
Captan EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Captan do in cosmetics?
Captan functions as: N-(Trichloromethylthio)-4-cyclohexene-1,2-dicarboximide; fungicide/pesticide. It is classified as a cosmetic ingredient in our database. CAS number: 133-06-2.
What is the Margin of Safety for Captan?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Captan?
The NOAEL (No Observed Adverse Effect Level) for Captan is 300 mg/kg bw/day based on a oral study via oral route in dog. A total of 2 study endpoints are available. Source: REACH.
Is Captan classified as hazardous under GHS?
Captan carries a GHS signal word of "WARNING". Hazard statements: Causes skin and eye irritation May cause an allergic skin reaction Very toxic to aquatic life. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance — at cosmetic use concentrations, hazard thresholds may not be met.
Compliance Tools
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Related Ingredients
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