Good Emollient NOAEL Data GHS Classified

Castor Oil (Ricinus Communis Seed Oil)

INCI: RICINUS COMMUNIS SEED OIL

CAS Number
8001-79-4
Function
Emollient
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
EU Max Conc. 16%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Castor Oil (Ricinus Communis Seed Oil). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 3045 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 7823 mg/kg bw/day oral mouse Subchronic COSMOS_DB
NOAEL 12840 mg/kg bw/day oral rat Special Toxicology Study COSMOS_DB
NOAEL 12840 mg/kg bw/day oral rat Special Toxicology Study COSMOS_DB
NOAEL 11329 mg/kg bw/day oral rat Special Toxicology Study COSMOS_DB
NOAEL 10 other oral rat oral REACH
NOAEL 10 other oral mouse oral REACH
NOAEL >=15 other oral rat oral REACH
NOAEL 200000 mg/kg bw/day oral rat oral REACH
NOAEL 1000 mg/kg bw/day oral rat oral REACH

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is irritating to the gastrointestinal tract.
Long-term Exposure Effects
Repeated or prolonged contact with skin may cause dermatitis.

Expert Verdict

Good safety profile. Generally considered safe for cosmetic use.

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Concern Level: Low

Regulatory Flags

epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Castor Oil (Ricinus Communis Seed Oil) safe in cosmetics?

Good safety profile. Generally considered safe for cosmetic use. The EU classifies Castor Oil (Ricinus Communis Seed Oil) as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.

Is Castor Oil (Ricinus Communis Seed Oil) allowed in the EU?

Castor Oil (Ricinus Communis Seed Oil) EU regulatory status: permitted. Maximum allowed concentration: 16%. This is based on EU Regulation 1223/2009 and its amendments.

What does Castor Oil (Ricinus Communis Seed Oil) do in cosmetics?

Castor Oil (Ricinus Communis Seed Oil) functions as: Emollient. It is classified as a Emollient in our database. CAS number: 8001-79-4.

What is the Margin of Safety for Castor Oil (Ricinus Communis Seed Oil)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Castor Oil (Ricinus Communis Seed Oil)?

The NOAEL (No Observed Adverse Effect Level) for Castor Oil (Ricinus Communis Seed Oil) is 3045 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.

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