Ceramide 1 A

INCI: CERAMIDE 1 A

CAS Number
179186-48-2
Function
Hair conditioning; skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed. Reported in FDA VCRP data in eye lotions (5 products), mascara (3 products), foundations (3 products), and other product categories

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No significant safety concerns reported. Ceramides as a class are naturally present in the stratum corneum and are generally well-tolerated. No irritation or sensitization issues documented at cosmetic use levels. Molecular weight 988.6 g/mol. Chemical name: Linoleoyloxyheptacosanoyl-C18-phytosphingosine. Integrates into the skin's intercellular lipid matrix and forms lamellar structures between corneocytes, reducing TEWL. Meta-analysis shows ceramide-containing moisturizers significantly imp...

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Concern Level: Moderate

Regulatory Flags

potential-allergen natural-origin

Frequently Asked Questions

Is Ceramide 1 A safe in cosmetics?

No significant safety concerns reported. Ceramides as a class are naturally present in the stratum corneum and are generally well-tolerated. No irritation or sensitization issues documented at cosmetic use levels. Molecular weight 988.6 g/mol. Chemical name: Linoleoyloxyheptacosanoyl-C18-phytosphingosine. Integrates into the skin's intercellular lipid matrix and forms lamellar structures between corneocytes, reducing TEWL. Meta-analysis shows ceramide-containing moisturizers significantly imp... The EU classifies Ceramide 1 A as "permitted". Safety rating: MODERATE.

Is Ceramide 1 A allowed in the EU?

Ceramide 1 A EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ceramide 1 A do in cosmetics?

Ceramide 1 A functions as: Hair conditioning; skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 179186-48-2.

What is the Margin of Safety for Ceramide 1 A?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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