Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Cetearyl Isononanoate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 300 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 300 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
CIR concluded safe as used when formulated to be non-irritating. Human patch tests and RIPT data show excellent skin compatibility up to 100%.
Frequently Asked Questions
Is Cetearyl Isononanoate safe in cosmetics?
CIR concluded safe as used when formulated to be non-irritating. Human patch tests and RIPT data show excellent skin compatibility up to 100%. The EU classifies Cetearyl Isononanoate as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.
Is Cetearyl Isononanoate allowed in the EU?
Cetearyl Isononanoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cetearyl Isononanoate do in cosmetics?
Cetearyl Isononanoate functions as: Emollient. It is classified as a Emollient in our database. CAS number: 111937-03-2.
What is the Margin of Safety for Cetearyl Isononanoate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Cetearyl Isononanoate?
The NOAEL (No Observed Adverse Effect Level) for Cetearyl Isononanoate is 1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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