Chlorosalicylic Acid

INCI: CHLOROSALICYLIC ACID

CAS Number
321-14-2 (5-chlorosalicylic acid)
Function
Antimicrobial / keratolytic (salicylic acid derivative)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes YELLOW

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Chlorosalicylic acid is a salicylic acid derivative with potential CMR classification concerns; requires dedicated toxicological dossier as it is not covered by existing SCCS salicylic acid safety opinions.

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Concern Level: High

Frequently Asked Questions

Is Chlorosalicylic Acid safe in cosmetics?

Chlorosalicylic acid is a salicylic acid derivative with potential CMR classification concerns; requires dedicated toxicological dossier as it is not covered by existing SCCS salicylic acid safety opinions. The EU classifies Chlorosalicylic Acid as "prohibited". Safety rating: MODERATE.

Is Chlorosalicylic Acid allowed in the EU?

Chlorosalicylic Acid EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Chlorosalicylic Acid do in cosmetics?

Chlorosalicylic Acid functions as: Antimicrobial / keratolytic (salicylic acid derivative). It is classified as a cosmetic ingredient in our database. CAS number: 321-14-2 (5-chlorosalicylic acid).

What is the Margin of Safety for Chlorosalicylic Acid?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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