CHLORHEXIDINE DIACETATE

CAS Number
56-95-1
Function
Antimicrobial, Oral Care, Preservative
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Restricted
EU Max Conc. V/42
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes CIR: SQ - IJT 30(Suppl. 2):73-127, 2011

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
NOAEL: 250 (dermal systemic) mg/kg bw/day | Source: Chlorhexidine: Human health tier II assessment (NICNAS/industrial chemicals authority), 2015 (sum...

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CHLORHEXIDINE DIACETATE is listed in the EU CosIng database with functions: Antimicrobial, Oral Care, Preservative It is restricted under EU Cosmetics Regulation. Restriction: V/42.

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Concern Level: Medium

Regulatory Flags

cosing-sourced eu-restricted preservative needs-enrichment

Frequently Asked Questions

Is CHLORHEXIDINE DIACETATE safe in cosmetics?

CHLORHEXIDINE DIACETATE is listed in the EU CosIng database with functions: Antimicrobial, Oral Care, Preservative It is restricted under EU Cosmetics Regulation. Restriction: V/42. The EU classifies CHLORHEXIDINE DIACETATE as "Restricted". Safety rating: MODERATE.

Is CHLORHEXIDINE DIACETATE allowed in the EU?

CHLORHEXIDINE DIACETATE EU regulatory status: Restricted. Maximum allowed concentration: V/42. This is based on EU Regulation 1223/2009 and its amendments.

What does CHLORHEXIDINE DIACETATE do in cosmetics?

CHLORHEXIDINE DIACETATE functions as: Antimicrobial, Oral Care, Preservative. It is classified as a cosmetic ingredient in our database. CAS number: 56-95-1.

What is the Margin of Safety for CHLORHEXIDINE DIACETATE?

NOAEL: 250 (dermal systemic) mg/kg bw/day | Source: Chlorhexidine: Human health tier II assessment (NICNAS/industrial chemicals authority), 2015 (sum... The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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