Cholesteryl Oleate

INCI: CHOLESTERYL OLEATE

CAS Number
303-43-5
Function
Skin conditioning agent (emollient); lipid-identical component found in skin surface lipids
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA permitted for cosmetic use; no restrictions. Not CIR-reviewed as standalone, but parent cholesterol assessed safe as used (CIR 1986, reaffirmed 2004, 2024 re-review)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No safety concerns identified at cosmetic use levels. Potential for oxidized cholesterol byproducts if exposed to heat or UV during storage.

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Concern Level: Low

Frequently Asked Questions

Is Cholesteryl Oleate safe in cosmetics?

No safety concerns identified at cosmetic use levels. Potential for oxidized cholesterol byproducts if exposed to heat or UV during storage. The EU classifies Cholesteryl Oleate as "permitted". Safety rating: GOOD.

Is Cholesteryl Oleate allowed in the EU?

Cholesteryl Oleate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cholesteryl Oleate do in cosmetics?

Cholesteryl Oleate functions as: Skin conditioning agent (emollient); lipid-identical component found in skin surface lipids. It is classified as a cosmetic ingredient in our database. CAS number: 303-43-5.

What is the Margin of Safety for Cholesteryl Oleate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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