Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
ne ingredients as used in cosmetic formulations. The Panel concluded that these 4 Ubiquinone ingredients are safe in the present practices of use and concentrations described in this safety assessment. The Panel noted that Hydroxydecyl Ubiquinone is a synthetic analog of Ubiquinone with a shorter chain structu
ne ingredients as used in cosmetic formulations. The Panel concluded that these 4 Ubiquinone ingredients are safe in the present practices of use and concentrations described in this safety assessment. The Panel noted that Hydroxydecyl Ubiquinone is a synthetic analog of Ubiquinone with a shorter chain structu
ne ingredients as used in cosmetic formulations. The Panel concluded that these 4 Ubiquinone ingredients are safe in the present practices of use and concentrations described in this safety assessment. The Panel noted that Hydroxydecyl Ubiquinone is a synthetic analog of Ubiquinone with a shorter chain structu
ne ingredients as used in cosmetic formulations. The Panel concluded that these 4 Ubiquinone ingredients are safe in the present practices of use and concentrations described in this safety assessment. The Panel noted that Hydroxydecyl Ubiquinone is a synthetic analog of Ubiquinone with a shorter chain structu
ne ingredients as used in cosmetic formulations. The Panel concluded that these 4 Ubiquinone ingredients are safe in the present practices of use and concentrations described in this safety assessment. The Panel noted that Hydroxydecyl Ubiquinone is a synthetic analog of Ubiquinone with a shorter chain structu
Expert Verdict
Ubiquinone addresses mitochondrial protection against pollution-induced oxidative stress, a mechanism most other antioxidants do not target; endogenous coenzyme with established safety profile and no sensitization concerns; topical supplementation at 0.01–0.5% restores mitochondrial resilience to pollution and HEV-induced damage, particularly beneficial for age-related decline in 35+ demographics when combined with vitamin E and ferulic acid in oil-based formulations.
Regulatory Flags
Frequently Asked Questions
Is Ubiquinone safe in cosmetics?
Ubiquinone addresses mitochondrial protection against pollution-induced oxidative stress, a mechanism most other antioxidants do not target; endogenous coenzyme with established safety profile and no sensitization concerns; topical supplementation at 0.01–0.5% restores mitochondrial resilience to pollution and HEV-induced damage, particularly beneficial for age-related decline in 35+ demographics when combined with vitamin E and ferulic acid in oil-based formulations. The EU classifies Ubiquinone as "permitted". Safety rating: EXCELLENT. This ingredient has been reviewed by cir.
Is Ubiquinone allowed in the EU?
Ubiquinone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ubiquinone do in cosmetics?
Ubiquinone functions as: Antioxidant; mitochondrial electron transport chain protector; anti-pollution active; HEV mitochondrial stress protectant; endogenous lipophilic antioxidant; energy metabolism cofactor. It is classified as a Antioxidant in our database. CAS number: 303-98-0.
What is the Margin of Safety for Ubiquinone?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Ubiquinone compliance across multiple jurisdictions:
Related Ingredients
Is Ubiquinone in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Ubiquinone in your formulation.