Good Cosmetic Ingredient

CI 40820 (8'-Apo-Beta-Caroten-8'-al / Apocarotenal)

INCI: CI 40820

CAS Number
1962-15-8
Function
Colorant. Synthetic carotenoid colorant (8'-Apo-Beta-Caroten-8'-al, also known as Apocarotenal and E160e). Imparts orange-to-red coloration to cosmetic products. Related structurally to beta-carotene; a naturally occurring oxidative cleavage product of beta-carotene found in citrus fruits and spinach. Used as a colorant in all cosmetic product types. Functions as an antioxidant in addition to its primary coloring function.
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
EU Max Conc. Listed in Annex IV of EU Cosmetics Regulation (EC) No. 1223/2009 (Entry IV/56). Permitted as a colorant in all cosmetic products without a specified maximum concentration.
🇺🇸 US Status restricted
US Notes Not listed as an FDA-certified or exempt color additive for cosmetics under 21 CFR Parts 73, 74, or 82. CI 40820 (Apocarotenal / E160e) does not appear on the FDA Color Additives Permitted for Use in Cosmetics list. Use in US cosmetics is not explicitly authorized by FDA; formulators should verify regulatory status prior to marketing in the US market.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CI 40820 is a carotenoid colorant approved under EU Annex IV Entry IV/56 for use in all cosmetic products, with a favorable safety profile based on its beta-carotene analog structure and food-use history as E160e; however, it lacks explicit FDA authorization in the US and is not on the permitted cosmetic color additives list.

⚠️
Concern Level: Low

Regulatory Flags

eu-annex-iv not-fda-listed all-cosmetics-eu carotenoid food-additive-e160e antioxidant no-concentration-limit-eu us-regulatory-gap purity-criteria-required

Frequently Asked Questions

Is CI 40820 (8'-Apo-Beta-Caroten-8'-al / Apocarotenal) safe in cosmetics?

CI 40820 is a carotenoid colorant approved under EU Annex IV Entry IV/56 for use in all cosmetic products, with a favorable safety profile based on its beta-carotene analog structure and food-use history as E160e; however, it lacks explicit FDA authorization in the US and is not on the permitted cosmetic color additives list. The EU classifies CI 40820 (8'-Apo-Beta-Caroten-8'-al / Apocarotenal) as "permitted". Safety rating: GOOD.

Is CI 40820 (8'-Apo-Beta-Caroten-8'-al / Apocarotenal) allowed in the EU?

CI 40820 (8'-Apo-Beta-Caroten-8'-al / Apocarotenal) EU regulatory status: permitted. Maximum allowed concentration: Listed in Annex IV of EU Cosmetics Regulation (EC) No. 1223/2009 (Entry IV/56). Permitted as a colorant in all cosmetic products without a specified maximum concentration.. This is based on EU Regulation 1223/2009 and its amendments.

What does CI 40820 (8'-Apo-Beta-Caroten-8'-al / Apocarotenal) do in cosmetics?

CI 40820 (8'-Apo-Beta-Caroten-8'-al / Apocarotenal) functions as: Colorant. Synthetic carotenoid colorant (8'-Apo-Beta-Caroten-8'-al, also known as Apocarotenal and E160e). Imparts orange-to-red coloration to cosmetic products. Related structurally to beta-carotene; a naturally occurring oxidative cleavage product of beta-carotene found in citrus fruits and spinach. Used as a colorant in all cosmetic product types. Functions as an antioxidant in addition to its primary coloring function.. It is classified as a cosmetic ingredient in our database. CAS number: 1962-15-8.

What is the Margin of Safety for CI 40820 (8'-Apo-Beta-Caroten-8'-al / Apocarotenal)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check CI 40820 (8'-Apo-Beta-Caroten-8'-al / Apocarotenal) compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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