Is CI 45425 safe in cosmetics?
CI 45425 has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: prohibited.
Moderate
Cosmetic Ingredient
CI 45425
Also known as: Fluorescein, 4,7-dichloro-2',4',5',7'-tetrabromo-, dipotassium salt, Dipotassium 3,6-dichloro-2-(2,4,5,7-tetrabromo-6-oxido-3-oxoxanthen-9-yl)benzoate, Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 2',4',5',7'-tetrabromo-4,7-dichloro-3',6'-dihydroxy-, dipotassium salt, Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 2',4',5',7'-tetrabromo-4,7-dichloro-3',6'-dihydroxy-, potassium salt (1:2), Phloxine (+4 more)
INCI: ACID RED 98
CI 45425 (CAS 6441-77-6) is a cosmetic cosmetic ingredient functioning as Colorant (red xanthene dye). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 6441-77-6 →
Auto-generated CPSR Part A draft with source citations
Function
Colorant (red xanthene dye)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
dipotassium;2',4',5',7'-tetrabromo-4,7-dichloro-3-oxospiro[2-benzofuran-1,9'-xanthene]-3',6'-diolate
InChIKey
JBBPTUVOZCXCSU-UHFFFAOYSA-L
Regulatory Status
EU EU Status
prohibited
US US Status
prohibited
US Notes
Not listed as a permitted color additive for cosmetics by FDA
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for CI 45425.
Calculate MoS for your specific formulation with the MoS Calculator.
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex IV — Permitted Colorants
Product type: Red
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (IV - Colorants)
Product type: Not to be used in eye products.
BRIN Brazil/India Cosmetics
India: Permitted Colorant
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Expert Verdict
Expert safety assessment and concern-level summary for CI 45425.
Regulatory Flags
colorant
Known Synonyms
Fluorescein, 4,7-dichloro-2',4',5',7'-tetrabromo-, dipotassium salt
Dipotassium 3,6-dichloro-2-(2,4,5,7-tetrabromo-6-oxido-3-oxoxanthen-9-yl)benzoate
Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 2',4',5',7'-tetrabromo-4,7-dichloro-3',6'-dihydroxy-, dipotassium salt
Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 2',4',5',7'-tetrabromo-4,7-dichloro-3',6'-dihydroxy-, potassium salt (1:2)
Phloxine
C.I. 45405
C.I. Acid Red 98
Phloxin
Toyo Acid Phloxine
Chemical Function
Dye
Frequently Asked Questions
Is CI 45425 allowed in the EU?
CI 45425 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does CI 45425 do in cosmetics?
CI 45425 functions as: Colorant (red xanthene dye). It is classified as a cosmetic ingredient in our database. CAS number: 6441-77-6.
Compliance Tools
Check CI 45425 compliance across multiple jurisdictions:
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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