Moderate Cosmetic Ingredient NOAEL Data

CI 60724

Also known as: 1,4-Diamino-2,3-diphenoxy-9,10-anthracenedione, EINECS 229-066-0, C.I. Disperse Violet 31, C.I. Solvent Violet 59, Solvaperm Red Violet R (+2 more)

INCI: SOLVENT VIOLET 13

CI 60724 (CAS 6408-72-6) is a cosmetic cosmetic ingredient functioning as Colorant (violet anthraquinone dye). Reported NOAEL =1000 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 6408-72-6 →

Auto-generated CPSR Part A draft with source citations
Function
Colorant (violet anthraquinone dye)
Safety Rating
MODERATE

Chemistry & Identifiers

Formula
C26H18N2O4
MW
422.4 g/mol
EC Number
229-066-0
PubChem CID
80839
IUPAC Name
1,4-diamino-2,3-diphenoxyanthracene-9,10-dione
InChIKey
NZTGGRGGJFCKGG-UHFFFAOYSA-N

Regulatory Status

EU EU Status restricted
US US Status prohibited
US Notes Not listed as a separately permitted color additive in FDA tables for cosmetics.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for CI 60724.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for CI 60724. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =1000 mg/kg bw/day oral Rat short-term ToxValDB_ECHA_IUCLID

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Expanded Jurisdictional Detail

Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.

Additional Jurisdictional Restrictions (1)
Jurisdiction Status Max % Product Type
ASEAN permitted_colorant - Not eye area

PubChem Annotations

Safety and regulatory annotations from PubChem (NCBI) aggregated sources.

Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Dye Fragrance
Regulatory List Membership (1)
IFRA Fragrance Transparency List

Expert Verdict

Expert safety assessment and concern-level summary for CI 60724.

Regulatory Flags

colorant ifra_fragrance

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to CI 60724 by CAS number or substance name.

Studies
1
Lowest NOAEL
1000 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Known Synonyms

1,4-Diamino-2,3-diphenoxy-9,10-anthracenedione EINECS 229-066-0 C.I. Disperse Violet 31 C.I. Solvent Violet 59 Solvaperm Red Violet R Red Violet R Solvent Violet 59

Chemical Function

Fragrance Dye

Regulatory Lists

IFRA Transparency

Australian Status

AICIS status: listed

Frequently Asked Questions

Is CI 60724 safe in cosmetics?

CI 60724 has a safety rating of "MODERATE" in our database. EU status: restricted. US status: prohibited. 1 toxicological study endpoint(s) are available in our database.

Is CI 60724 allowed in the EU?

CI 60724 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does CI 60724 do in cosmetics?

CI 60724 functions as: Colorant (violet anthraquinone dye). It is classified as a cosmetic ingredient in our database. CAS number: 6408-72-6.

What is the NOAEL for CI 60724?

The NOAEL (No Observed Adverse Effect Level) for CI 60724 is =1000 mg/kg bw/day based on a short-term study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.

Is CI 60724 used outside cosmetics?

CI 60724 also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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