Good Cosmetic Ingredient

CI 75300 (Curcumin)

INCI: CI 75300

CAS Number

458-37-7

Function

Colorant. Natural polyphenol pigment extracted from the rhizome of Curcuma longa (turmeric); also known as Curcumin, Natural Yellow 3, and food colorant E100. Imparts bright yellow-orange coloration to cosmetic products. Water-soluble and fat-soluble forms available.

Safety Rating

GOOD

Regulatory Status

🇪🇺 EU Status permitted

🇺🇸 US Status prohibited

US Notes FDA delisted Curcumin as a color additive effective July 2, 1966 (31 FR 9105) after it was only provisionally listed for food use with no ongoing commercial interest. Curcumin is not listed in 21 CFR Parts 73 or 74 as an approved color additive for cosmetics or drugs. While curcumin may be used as a cosmetic ingredient for its functional properties (antioxidant, skin-conditioning), its use as a declared color additive in US cosmetics is not formally supported under FDA color additive regulations.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)

not established

Dermal Absorption

moderate

Sensitization

low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CI 75300 (Curcumin / Natural Yellow 3) is a natural turmeric-derived colorant permitted in EU cosmetics (Annex IV, Restriction IV/114) but delisted by the FDA in 1966 and not formally approved for use as a color additive in US cosmetics; it has a favorable safety profile with low sensitization risk at typical cosmetic concentrations.

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Concern Level: Low

Regulatory Flags

natural-colorant polyphenol eu-annex-iv turmeric-derived e100 fda-delisted-1966 not-fda-cosmetic-color-listing antioxidant anti-inflammatory food-grade-origin

Frequently Asked Questions

Is CI 75300 (Curcumin) safe in cosmetics?

Is CI 75300 (Curcumin) allowed in the EU?

CI 75300 (Curcumin) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does CI 75300 (Curcumin) do in cosmetics?

CI 75300 (Curcumin) functions as: Colorant. Natural polyphenol pigment extracted from the rhizome of Curcuma longa (turmeric); also known as Curcumin, Natural Yellow 3, and food colorant E100. Imparts bright yellow-orange coloration to cosmetic products. Water-soluble and fat-soluble forms available.. It is classified as a cosmetic ingredient in our database. CAS number: 458-37-7.

What is the Margin of Safety for CI 75300 (Curcumin)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check CI 75300 (Curcumin) compliance across multiple jurisdictions:

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Ingredient Decoder

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82 Allergen Checker

Check for EU declarable fragrance allergens

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Substance Compliance

Check compliance across 55 jurisdictions

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MoS Calculator

Calculate Margin of Safety using SCCS methodology

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Heavy Metal Limits

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