Ciclopirox Olamine

INCI: CICLOPIROX OLAMINE

CAS Number
41621-49-2
Function
Anti-dandruff agent (antimicrobial/antifungal)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted in cosmetics; also an OTC/Rx antifungal drug ingredient (FDA monograph)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Secondary amine/alkanolamine content requires compliance with Annex III nitrosamine formation limits and purity criteria.

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Concern Level: Moderate

Frequently Asked Questions

Is Ciclopirox Olamine safe in cosmetics?

Secondary amine/alkanolamine content requires compliance with Annex III nitrosamine formation limits and purity criteria. The EU classifies Ciclopirox Olamine as "restricted". Safety rating: MODERATE.

Is Ciclopirox Olamine allowed in the EU?

Ciclopirox Olamine EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ciclopirox Olamine do in cosmetics?

Ciclopirox Olamine functions as: Anti-dandruff agent (antimicrobial/antifungal). It is classified as a cosmetic ingredient in our database. CAS number: 41621-49-2.

What is the Margin of Safety for Ciclopirox Olamine?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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