Cinchona Pubescens Bark Extract

INCI: CINCHONA PUBESCENS BARK EXTRACT

CAS Number
Not specifically assigned (genus-level CAS 68990-12-5 covers Cinchona spp.)
Function
Skin conditioning, astringent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted in cosmetics; Cinchona spp. recognized by FDA

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Pharmacologically active quinine alkaloids present; Red Cinchona particularly high in quinine content with sensitization and photosensitivity risk.

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Concern Level: Moderate

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Cinchona Pubescens Bark Extract safe in cosmetics?

Pharmacologically active quinine alkaloids present; Red Cinchona particularly high in quinine content with sensitization and photosensitivity risk. The EU classifies Cinchona Pubescens Bark Extract as "prohibited". Safety rating: MODERATE.

Is Cinchona Pubescens Bark Extract allowed in the EU?

Cinchona Pubescens Bark Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Cinchona Pubescens Bark Extract do in cosmetics?

Cinchona Pubescens Bark Extract functions as: Skin conditioning, astringent. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned (genus-level CAS 68990-12-5 covers Cinchona spp.).

What is the Margin of Safety for Cinchona Pubescens Bark Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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