Is Citronellyl Isobutyrate safe in cosmetics?
Citronellyl Isobutyrate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Citronellyl Isobutyrate
Also known as: 3,7-Dimethyloct-6-enyl isobutyrate, Citronellyl 2-methylpropanoate, 3,7-Dimethyl-6-octenyl isobutyrate, 3,7-Dimethyl-6-octen-1-yl isobutyrate, 3,7-Dimethyl-6-octen-1-yl 2-methylpropanoate (+6 more)
INCI: CITRONELLYL ISOBUTYRATE
Citronellyl Isobutyrate (CAS 97-89-2) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient with fresh, citrusy-rosy, fruity-sweet profile. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 97-89-2 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient with fresh, citrusy-rosy, fruity-sweet profile
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
3,7-dimethyloct-6-enyl 2-methylpropanoate
InChIKey
ZGPPERKMXSGYRK-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR deferred to RIFM; FEMA GRAS listed
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Citronellyl Isobutyrate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 2592 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
Ceased manufacture
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
71
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
CITRONELLYL ISOBUTYRATE | 2002 | No safety concern at current levels of intake when used as a flavouring agent | Secondary components do not raise a safety concern | TRS 913-JECFA 59/111 | FAS 40-JECFA 49/329 (1997)
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Citronellyl Isobutyrate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
3,7-Dimethyloct-6-enyl isobutyrate
Citronellyl 2-methylpropanoate
3,7-Dimethyl-6-octenyl isobutyrate
3,7-Dimethyl-6-octen-1-yl isobutyrate
3,7-Dimethyl-6-octen-1-yl 2-methylpropanoate
3,7-Dimethyl-6-octenyl methylpropionate
EINECS 202-616-7
FEMA No. 2313
Isobutyric acid, 3,7-dimethyl-6-octenyl ester
NSC 46148
UNII-5RZR3JKW1P
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
CITRONELLYL ISOBUTYRATE
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is Citronellyl Isobutyrate allowed in the EU?
Citronellyl Isobutyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Citronellyl Isobutyrate do in cosmetics?
Citronellyl Isobutyrate functions as: Fragrance ingredient with fresh, citrusy-rosy, fruity-sweet profile. It is classified as a cosmetic ingredient in our database. CAS number: 97-89-2.
Is Citronellyl Isobutyrate used outside cosmetics?
Citronellyl Isobutyrate also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Citronellyl Isobutyrate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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