Citrus Aurantium Leaf Extract

INCI: CITRUS AURANTIUM LEAF EXTRACT

CAS Number
72968-50-4 (generic bitter orange)
Function
Skin conditioning, antioxidant, fragrance
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not restricted; CIR data insufficient for standalone determination

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Synephrine content possible (bitter orange leaf contains trace sympathomimetic amines); verify if intended for leave-on or oral-adjacent products; allergen declaration required.

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Concern Level: Low

Regulatory Flags

plant-extract potential-allergen fragrance-component

Frequently Asked Questions

Is Citrus Aurantium Leaf Extract safe in cosmetics?

Synephrine content possible (bitter orange leaf contains trace sympathomimetic amines); verify if intended for leave-on or oral-adjacent products; allergen declaration required. The EU classifies Citrus Aurantium Leaf Extract as "permitted". Safety rating: GOOD.

Is Citrus Aurantium Leaf Extract allowed in the EU?

Citrus Aurantium Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Citrus Aurantium Leaf Extract do in cosmetics?

Citrus Aurantium Leaf Extract functions as: Skin conditioning, antioxidant, fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 72968-50-4 (generic bitter orange).

What is the Margin of Safety for Citrus Aurantium Leaf Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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