Citrus Grandis Peel/Seed Extract

INCI: CITRUS GRANDIS PEEL/SEED EXTRACT

CAS Number
Not specifically assigned; parent: 90045-43-5 (generic Citrus grandis)
Function
Antifungal agents, antimicrobial agents, preservatives
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA does not pre-approve. Used in cosmetics as a self-preserving aid. Not an official FDA-recognized preservative. Some commercial grapefruit seed extracts have been found to contain synthetic antimicrobials (e.g., benzethonium chloride, methylparaben) as adulterants โ€” supply chain verification critical.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Not an EU Annex V-approved preservative; do not claim preservative function in EU markets. Adulteration risk with synthetic antimicrobials in commercial grapefruit seed extract products must be verified by supplier certificate of analysis. Must control 5-MOP at 15 ppm or below. Allergen labeling requirements apply.

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Concern Level: Moderate

Regulatory Flags

plant-extract potential-allergen preservative

Frequently Asked Questions

Is Citrus Grandis Peel/Seed Extract safe in cosmetics?

Not an EU Annex V-approved preservative; do not claim preservative function in EU markets. Adulteration risk with synthetic antimicrobials in commercial grapefruit seed extract products must be verified by supplier certificate of analysis. Must control 5-MOP at 15 ppm or below. Allergen labeling requirements apply. The EU classifies Citrus Grandis Peel/Seed Extract as "prohibited". Safety rating: GOOD.

Is Citrus Grandis Peel/Seed Extract allowed in the EU?

Citrus Grandis Peel/Seed Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Citrus Grandis Peel/Seed Extract do in cosmetics?

Citrus Grandis Peel/Seed Extract functions as: Antifungal agents, antimicrobial agents, preservatives. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned; parent: 90045-43-5 (generic Citrus grandis).

What is the Margin of Safety for Citrus Grandis Peel/Seed Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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