Moderate Cosmetic Ingredient Sensitization Data

Citrus Limon Peel Oil

Also known as: Citrus medica var. limonum oil, FEMA No. 2853, Petitgrain lemon oil (Citrus limon (L.) Burm. f.), Zitronen oel, UNII-I9GRO824LL (+1 more)

INCI: CITRUS LIMON PEEL OIL

Citrus Limon Peel Oil (CAS 8008-56-8) is a cosmetic cosmetic ingredient functioning as Fragrance, Skin Conditioning. NOAEL 5 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: restricted, max Annex III Entry 353: declare if >0.001% leave-on or >0.01% rinse-off. Furocoumarin <1 mg/kg in sun-protection. Max 15 ppm 5-MOP in leave-on.. Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS 8008-56-8 →

Auto-generated CPSR Part A draft with source citations
Function
Fragrance, Skin Conditioning
Safety Rating
MODERATE

Chemistry & Identifiers

Regulatory Status

EU EU Status restricted
EU Max Conc. Annex III Entry 353: declare if >0.001% leave-on or >0.01% rinse-off. Furocoumarin <1 mg/kg in sun-protection. Max 15 ppm 5-MOP in leave-on.
US US Status permitted
US Notes GRAS for food (21 CFR 182.20); CIR safe if ≤15 ppm 5-MOP in finished products and formulated to be non-sensitizing

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Citrus Limon Peel Oil.

Calculate MoS for your specific formulation with the MoS Calculator.

Pre-Calculated Safety Assessment

Pre-calculated NOAEL → SED → MoS audit trail for Citrus Limon Peel Oil across SCCS product categories, with measured dermal absorption where available.

Sensitization Profile

Contact sensitization data for Citrus Limon Peel Oil based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
fragrance
EU Allergen Listed
no
Patch Test Positive Rate
0.3%
Cross-reactivity Group
terpene-hydroperoxide-group
Reaction Type
contact-dermatitis
IFRA Restricted

Source: IFRA

EPA ToxValDB — Toxicity Values

1 toxicity value from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).

Endpoint Value Species Route Duration Source
LD50 =2840 mg/kg Rat oral - TEST

Additional Ingredient Properties

1 property record from structured ingredient metadata.

allergen_detail
{"eu_allergen_listed": "no", "allergen_class": "fragrance", "cross_reactivity_group": "terpene-hydroperoxide-group", "patch_test_frequency_pct": "0.3", "sensitization_rate": "low", "common_reaction_type": "contact-dermatitis", "ifra_restricted": "yes", "source": "IFRA"}

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Astringent Deodorizer Flavouring and nutrient Fragrance Humectant Softener and conditioner
Regulatory List Membership (4)
EU Regulated in Personal Care IFRA Fragrance Transparency List FDA Substances Added to Food (EAFUS) Consumer Product Chemical

Expert Verdict

Expert safety assessment and concern-level summary for Citrus Limon Peel Oil.

Regulatory Flags

EU_RESTRICTED CONTROVERSIAL ifra_fragrance fda_food_additive

Known Synonyms

Citrus medica var. limonum oil FEMA No. 2853 Petitgrain lemon oil (Citrus limon (L.) Burm. f.) Zitronen oel UNII-I9GRO824LL UNII-ET5GD00TRP

Chemical Function

Fragrance Astringent Deodorizer Humectant Softener and conditioner Flavouring and nutrient

Regulatory Lists

Europe; Personal care Europe; Personal care IFRA Transparency IFRA Transparency Europe; Personal care - body oil Australia; Food and drug - smoking-related products IFRA Transparency consumer_product IFRA Transparency IFRA Transparency IFRA Transparency IFRA Transparency IFRA Transparency food_additive; Substances Added to Food (formerly EAFUS) (2/2019) inert_ingredient; non_food_use; Pesticides Canada; consumer_product; Substances in Products - Canada (4/2014)

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Citrus Limon Peel Oil safe in cosmetics?

Citrus Limon Peel Oil has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.

Is Citrus Limon Peel Oil allowed in the EU?

Citrus Limon Peel Oil EU regulatory status: restricted. Maximum allowed concentration: Annex III Entry 353: declare if >0.001% leave-on or >0.01% rinse-off. Furocoumarin <1 mg/kg in sun-protection. Max 15 ppm 5-MOP in leave-on.. This is based on EU Regulation 1223/2009 and its amendments.

What does Citrus Limon Peel Oil do in cosmetics?

Citrus Limon Peel Oil functions as: Fragrance, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 8008-56-8.

Is Citrus Limon Peel Oil in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Citrus Limon Peel Oil in your formulation.