Clematis Apiifolia Extract

INCI: CLEMATIS APIIFOLIA EXTRACT

CAS Number
Not assigned
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no prohibition

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited safety data in the public domain; Ranunculaceae family plants contain protoanemonin, a known irritant-extract processing (solvent extraction) typically degrades this compound, but irritation potential should be patch-tested; no CIR (Cosmetic Ingredient Review) monograph available. Whole-plant extract of Clematis apiifolia (Ranunculaceae); traditionally used in East Asian herbal medicine; reported antioxidant response element activity

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Concern Level: Moderate

Regulatory Flags

plant-extract natural-origin

Frequently Asked Questions

Is Clematis Apiifolia Extract safe in cosmetics?

Limited safety data in the public domain; Ranunculaceae family plants contain protoanemonin, a known irritant-extract processing (solvent extraction) typically degrades this compound, but irritation potential should be patch-tested; no CIR (Cosmetic Ingredient Review) monograph available. Whole-plant extract of Clematis apiifolia (Ranunculaceae); traditionally used in East Asian herbal medicine; reported antioxidant response element activity The EU classifies Clematis Apiifolia Extract as "permitted". Safety rating: MODERATE.

Is Clematis Apiifolia Extract allowed in the EU?

Clematis Apiifolia Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Clematis Apiifolia Extract do in cosmetics?

Clematis Apiifolia Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Clematis Apiifolia Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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