Good Emollient NOAEL Data Sensitization Data

Coconut Oil (Cocos Nucifera Oil)

INCI: COCOS NUCIFERA OIL

CAS Number
8001-31-8
Function
Emollient
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Coconut Oil (Cocos Nucifera Oil). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 4850 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 20000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 1817 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 1777 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 1772 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 1780 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 10000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 4000 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 7000 mg/kg bw/day oral gerbil Short Term Toxicity COSMOS_DB
NOAEL 22500 mg/kg bw/day oral mouse Special Toxicology Study COSMOS_DB

Sensitization Profile

Contact sensitization data for Coconut Oil (Cocos Nucifera Oil) based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
botanical
EU Allergen Listed
no
Patch Test Positive Rate
0.1%
Cross-reactivity Group
none
Reaction Type
contact-dermatitis

Source: IVDK; literature review

Expert Verdict

Good safety profile with established use history in cosmetics.

โš ๏ธ
Concern Level: Low

Regulatory Flags

epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Coconut Oil (Cocos Nucifera Oil) safe in cosmetics?

Good safety profile with established use history in cosmetics. The EU classifies Coconut Oil (Cocos Nucifera Oil) as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.

Is Coconut Oil (Cocos Nucifera Oil) allowed in the EU?

Coconut Oil (Cocos Nucifera Oil) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Coconut Oil (Cocos Nucifera Oil) do in cosmetics?

Coconut Oil (Cocos Nucifera Oil) functions as: Emollient. It is classified as a Emollient in our database. CAS number: 8001-31-8.

What is the Margin of Safety for Coconut Oil (Cocos Nucifera Oil)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Coconut Oil (Cocos Nucifera Oil)?

The NOAEL (No Observed Adverse Effect Level) for Coconut Oil (Cocos Nucifera Oil) is 4850 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.

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