Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Coffea Arabica Seed Oil. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 33 mg/kg bw/day | oral | mouse | Special Toxicology Study | COSMOS_DB |
| NOAEL | 2500 mg/kg bw/day | oral | rat | Carcinogenicity | COSMOS_DB |
| NOAEL | 1483 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| NOAEL | 1716 mg/kg bw/day | oral | rat | Reproductive | COSMOS_DB |
| NOAEL | 1958 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 1931 mg/kg bw/day | oral | rat | Reproductive | COSMOS_DB |
| NOAEL | 2489 mg/kg bw/day | oral | rat | Reproductive-developmental | COSMOS_DB |
| NOAEL | 3750 mg/kg bw/day | oral | mouse | Carcinogenicity | COSMOS_DB |
| NOAEL | 3725 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| NOAEL | 3775 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
Expert Verdict
CIR Expert Panel concluded Coffea Arabica Seed Oil is safe as used in a group assessment of 244 plant-derived fatty acid oils. Topical coffee oil reduced UVB-induced wrinkle formation by over 35% and erythema by 48% in hairless mice.
Regulatory Flags
Frequently Asked Questions
Is Coffea Arabica Seed Oil safe in cosmetics?
CIR Expert Panel concluded Coffea Arabica Seed Oil is safe as used in a group assessment of 244 plant-derived fatty acid oils. Topical coffee oil reduced UVB-induced wrinkle formation by over 35% and erythema by 48% in hairless mice. The EU classifies Coffea Arabica Seed Oil as "permitted". Safety rating: EXCELLENT. 10 toxicological study endpoint(s) are available in our database.
Is Coffea Arabica Seed Oil allowed in the EU?
Coffea Arabica Seed Oil EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Coffea Arabica Seed Oil do in cosmetics?
Coffea Arabica Seed Oil functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84650-00-0.
What is the Margin of Safety for Coffea Arabica Seed Oil?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Coffea Arabica Seed Oil?
The NOAEL (No Observed Adverse Effect Level) for Coffea Arabica Seed Oil is 33 mg/kg bw/day based on a Special Toxicology Study study via oral route in mouse. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
Check Coffea Arabica Seed Oil compliance across multiple jurisdictions:
Related Ingredients
Is Coffea Arabica Seed Oil in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Coffea Arabica Seed Oil in your formulation.