Is Colloidal Oatmeal safe in cosmetics?
Colloidal Oatmeal has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Active Ingredient
Colloidal Oatmeal
Also known as: 1-Methyl-2-phenylthiomethyl-3-ethoxycarbonyl-5-hydroxy-6-bromoindole
INCI: AVENA SATIVA KERNEL FLOUR
Colloidal Oatmeal (CAS 131707-24-9) is a cosmetic active ingredient functioning as Skin Protectant, Anti-inflammatory, Antipruritic. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 131707-24-9 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Protectant, Anti-inflammatory, Antipruritic
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
ethyl 6-bromo-5-hydroxy-1-methyl-2-(phenylsulfanylmethyl)indole-3-carboxylate
InChIKey
DAFNNZWQTJQQAP-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
FDA Category I OTC Skin Protectant active ingredient under Final Monograph 21 CFR Part 347 (June 2003) and OTC Monograph M016 (updated Sept 2021). Approved concentration: minimum 0.007%. Approved indications: temporarily protects and helps relieve minor skin irritation and itching due to rashes, eczema, poison ivy/oak/sumac, and insect bites. Products marketed as OTC skin protectants are considered drugs under US law.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Colloidal Oatmeal.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Intermediate
Tonnage Band
Intermediate use only
Substance Type
SUBSTANCE
SVHC Candidate
No
Typical Use Concentrations
Reported concentration ranges per product category from SCCS/CIR/industry sources.
| Product Category | Typical Range | Max Reported | Source |
|---|---|---|---|
| Body Lotion | 1–5 | 10 | CIR/FDA OTC |
Expert Verdict
Expert safety assessment and concern-level summary for Colloidal Oatmeal.
Regulatory Flags
otc-drug-dual-status
oat-allergy-risk
atopic-dermatitis-caution
fda-category-i-skin-protectant
gras-food-grade
Known Synonyms
1-Methyl-2-phenylthiomethyl-3-ethoxycarbonyl-5-hydroxy-6-bromoindole
Regulatory Lists
pharmaceutical
Frequently Asked Questions
Is Colloidal Oatmeal allowed in the EU?
Colloidal Oatmeal EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Colloidal Oatmeal do in cosmetics?
Colloidal Oatmeal functions as: Skin Protectant, Anti-inflammatory, Antipruritic. It is classified as a Active Ingredient in our database. CAS number: 131707-24-9.
Is Colloidal Oatmeal used outside cosmetics?
Colloidal Oatmeal also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Colloidal Oatmeal compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Acetyl Tetrapeptide-5
Excellent
Same category
Anti-edema peptide for periorbital ar...
Activated Charcoal
Excellent
Same category
Adsorbent; skin cleanser; pore-cleans...
Adenosine
Excellent
Same category
Skin-conditioning agent, anti-aging, ...
Allantoin
Excellent
Same category
Skin conditioner, keratolytic, anti-i...
Alpha-Glucan Oligosaccharide
Excellent
Same category
prebiotic, skin-conditioning
Ascophyllum Nodosum Extract
Excellent
Same category
Skin Brightening, Tyrosinase Inhibito...
1-Methylhydantoin-2-imide (Creatinine)
Excellent
Similar safety
Skin conditioning (skin brightening/l...
2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol)
Excellent
Similar safety
Fragrance (perfuming), masking
2-Ethoxy-2,6,6-Trimethyl-9-Methylenebicyclo[3.3.1]Nonane (Boisiris™)
Excellent
Similar safety
Fragrance (rich woody, orris/iris roo...
2-Hydroxypropylcarbamato Amodimethicone
Excellent
Similar safety
Hair conditioning; modified aminosili...
2-O-Ethyl Ascorbic Acid
Excellent
Similar safety
Softener and conditioner
3 O Ethyl Ascorbic Acid
Excellent
Similar safety
Antioxidant; tyrosinase inhibitor; me...
COLA ACUMINATA SEED EXTRACT
Good
Browse nearby
Skin Conditioning
COLEUS FORSKOHLII ROOT EXTRACT
Good
Browse nearby
Humectant, Oral Care, Skin Conditioni...
COLLAGEN
Good
Browse nearby
Hair Conditioning, Moisturising, Skin...
Is Colloidal Oatmeal in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Colloidal Oatmeal in your formulation.