Moderate Cosmetic Ingredient NOAEL Data

Copper Glycinate

INCI: COPPER GLYCINATE

CAS Number
13479-54-4
Function
Buffering Agent; Skin Conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA - no specific restriction. Not reviewed by CIR. Copper glycinate is also used as a dietary supplement ingredient, which provides some systemic safety data.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Copper Glycinate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 2 2104 inhalation - inhalation REACH

Expert Verdict

H317 sensitizer alert with environmental toxicity concerns (H400). Typical cosmetic use at low concentrations (<0.5%) mitigates risk. pH-dependent stability requires justification in safety assessment.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Copper Glycinate safe in cosmetics?

H317 sensitizer alert with environmental toxicity concerns (H400). Typical cosmetic use at low concentrations (<0.5%) mitigates risk. pH-dependent stability requires justification in safety assessment. The EU classifies Copper Glycinate as "restricted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.

Is Copper Glycinate allowed in the EU?

Copper Glycinate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Copper Glycinate do in cosmetics?

Copper Glycinate functions as: Buffering Agent; Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 13479-54-4.

What is the Margin of Safety for Copper Glycinate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Copper Glycinate?

The NOAEL (No Observed Adverse Effect Level) for Copper Glycinate is 2 2104 based on a inhalation study via inhalation route in rat. Source: REACH.

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