Cucurbiturils
INCI: NO ESTABLISHED INCI NAME - CUCURBITURILS ARE NOT CURRENTLY REGISTERED IN COSING AS COSMETIC INGREDIENTS
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Limited toxicological data for dermal exposure; in vitro studies show generally low cytotoxicity for CB, but comprehensive dermal safety profiles are lacking; the pumpkin-shaped macrocyclic structure binds guest molecules very strongly, raising questions about unintended interactions. Synthetic macrocyclic molecules made from glycoluril and formaldehyde; barrel-shaped cavity capable of encapsulating small molecules with very high binding constants; CB is most water-soluble and most studied fo...
Regulatory Flags
Frequently Asked Questions
Is Cucurbiturils safe in cosmetics?
Limited toxicological data for dermal exposure; in vitro studies show generally low cytotoxicity for CB, but comprehensive dermal safety profiles are lacking; the pumpkin-shaped macrocyclic structure binds guest molecules very strongly, raising questions about unintended interactions. Synthetic macrocyclic molecules made from glycoluril and formaldehyde; barrel-shaped cavity capable of encapsulating small molecules with very high binding constants; CB is most water-soluble and most studied fo... The EU classifies Cucurbiturils as "permitted". Safety rating: MODERATE.
Is Cucurbiturils allowed in the EU?
Cucurbiturils EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cucurbiturils do in cosmetics?
Cucurbiturils functions as: Research-stage: molecular encapsulation, fragrance delivery, active-ingredient stabilization (not yet a standard cosmetic function). It is classified as a cosmetic ingredient in our database. CAS number: 80262-44-8 (cucurbituril); 259886-50-5 (cucurbituril) - the family includes CB through CB.
What is the Margin of Safety for Cucurbiturils?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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