Moderate Cosmetic Ingredient NOAEL Data

Curcuma Zedoaria Root Powder

INCI: CURCUMA ZEDOARIA ROOT POWDER

CAS Number
84961-49-9
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; no specific FDA restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Curcuma Zedoaria Root Powder. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 137 mg/kg bw/day oral rabbit Special Toxicology Study COSMOS_DB
NOAEL 1500 mg/kg bw/day oral rat Special Toxicology Study COSMOS_DB

Expert Verdict

Potential sensitizer from same botanical; inhalation risk if used in powder or spray products; particle size characterization needed; no cosmetic-specific safety review

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Concern Level: Moderate

Regulatory Flags

potential-allergen natural-origin fda_food_additive

Frequently Asked Questions

Is Curcuma Zedoaria Root Powder safe in cosmetics?

Potential sensitizer from same botanical; inhalation risk if used in powder or spray products; particle size characterization needed; no cosmetic-specific safety review The EU classifies Curcuma Zedoaria Root Powder as "permitted". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.

Is Curcuma Zedoaria Root Powder allowed in the EU?

Curcuma Zedoaria Root Powder EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Curcuma Zedoaria Root Powder do in cosmetics?

Curcuma Zedoaria Root Powder functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84961-49-9.

What is the Margin of Safety for Curcuma Zedoaria Root Powder?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Curcuma Zedoaria Root Powder?

The NOAEL (No Observed Adverse Effect Level) for Curcuma Zedoaria Root Powder is 137 mg/kg bw/day based on a Special Toxicology Study study via oral route in rabbit. A total of 2 study endpoints are available. Source: COSMOS_DB.

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