CYCLOTRISILOXANE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Toxicological Studies
3 study endpoints found for CYCLOTRISILOXANE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 250 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 25 mg/kg bw/day | oral | rat | oral | REACH |
| LOAEL | 1500 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
CYCLOTRISILOXANE is listed in the EU CosIng database with functions: Hair Conditioning, Skin Conditioning, Skin Conditioning - Emollient, Solvent It is permitted in the EU without specific restrictions.
Regulatory Flags
Frequently Asked Questions
Is CYCLOTRISILOXANE safe in cosmetics?
CYCLOTRISILOXANE is listed in the EU CosIng database with functions: Hair Conditioning, Skin Conditioning, Skin Conditioning - Emollient, Solvent It is permitted in the EU without specific restrictions. The EU classifies CYCLOTRISILOXANE as "Permitted". Safety rating: GOOD. 3 toxicological study endpoint(s) are available in our database.
Is CYCLOTRISILOXANE allowed in the EU?
CYCLOTRISILOXANE EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does CYCLOTRISILOXANE do in cosmetics?
CYCLOTRISILOXANE functions as: Hair Conditioning, Skin Conditioning, Skin Conditioning - Emollient, Solvent. It is classified as a cosmetic ingredient in our database. CAS number: 541-05-9.
What is the NOAEL for CYCLOTRISILOXANE?
The NOAEL (No Observed Adverse Effect Level) for CYCLOTRISILOXANE is 250 mg/kg bw/day based on a oral study via oral route in rat. A total of 3 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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