Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Primarily a research chemical with handling warnings; cytosine is not an established cosmetic ingredient and any cosmetic use would require full safety documentation and regulatory strategy to address potential genotoxicity concerns as a DNA base analogue.
Frequently Asked Questions
Is Cytosine safe in cosmetics?
Primarily a research chemical with handling warnings; cytosine is not an established cosmetic ingredient and any cosmetic use would require full safety documentation and regulatory strategy to address potential genotoxicity concerns as a DNA base analogue. The EU classifies Cytosine as "permitted". Safety rating: MODERATE.
Is Cytosine allowed in the EU?
Cytosine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cytosine do in cosmetics?
Cytosine functions as: Nucleobase; rarely used directly in cosmetics but may appear in biotech actives, DNA/RNA-based or cell communication concepts. It is classified as a cosmetic ingredient in our database. CAS number: 71‑30‑7.
What is the Margin of Safety for Cytosine?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Cytosine compliance across multiple jurisdictions:
Related Ingredients
Is Cytosine in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Cytosine in your formulation.