Davilla Rugosa Leaf Extract

INCI: DAVILLA RUGOSA LEAF EXTRACT

CAS Number
Not publicly listed in major databases
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no specific prohibition or restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited standalone toxicological data publicly available; no flagged issues. Marketed commercially as CollGuard by Silab. Demonstrated in vitro activity for protecting and stimulating the skin collagen network, anti-glycation, anti-MMP (matrix metalloproteinase inhibition), anti-free radical activity, and promotion of functional collagen neo-synthesis.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Davilla Rugosa Leaf Extract safe in cosmetics?

Limited standalone toxicological data publicly available; no flagged issues. Marketed commercially as CollGuard by Silab. Demonstrated in vitro activity for protecting and stimulating the skin collagen network, anti-glycation, anti-MMP (matrix metalloproteinase inhibition), anti-free radical activity, and promotion of functional collagen neo-synthesis. The EU classifies Davilla Rugosa Leaf Extract as "permitted". Safety rating: MODERATE.

Is Davilla Rugosa Leaf Extract allowed in the EU?

Davilla Rugosa Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Davilla Rugosa Leaf Extract do in cosmetics?

Davilla Rugosa Leaf Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly listed in major databases.

What is the Margin of Safety for Davilla Rugosa Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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