Decanenitrile

INCI: DECANENITRILE (SYNONYMS: DECANONITRILE, 1-CYANONONANE)

CAS Number
1975-78-6
Function
Fragrance / Perfuming
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Allowed. No specific prohibitions or restrictions for cosmetic use.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

RIFM Expert Panel concluded the material is safe under current use limits. Not genotoxic (read-across from dodecanenitrile, CAS 2437-25-4). Skin sensitization below the DST threshold (900 µg/cm²). NOAEL for developmental/reproductive toxicity = 250 mg/kg/day. Not PBT per IFRA Environmental Standards. Classified as harmful if swallowed (R22), irritating to skin and eyes (R36/38), and toxic to aquatic organisms (R51/53). Respiratory tract irritant.. Used at low concentrations exclusively as a f...

⚠️
Concern Level: High

Regulatory Flags

potential-allergen fragrance-component ifra_fragrance

Frequently Asked Questions

Is Decanenitrile safe in cosmetics?

RIFM Expert Panel concluded the material is safe under current use limits. Not genotoxic (read-across from dodecanenitrile, CAS 2437-25-4). Skin sensitization below the DST threshold (900 µg/cm²). NOAEL for developmental/reproductive toxicity = 250 mg/kg/day. Not PBT per IFRA Environmental Standards. Classified as harmful if swallowed (R22), irritating to skin and eyes (R36/38), and toxic to aquatic organisms (R51/53). Respiratory tract irritant.. Used at low concentrations exclusively as a f... The EU classifies Decanenitrile as "permitted". Safety rating: MODERATE.

Is Decanenitrile allowed in the EU?

Decanenitrile EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Decanenitrile do in cosmetics?

Decanenitrile functions as: Fragrance / Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 1975-78-6.

What is the Margin of Safety for Decanenitrile?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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