Is Decarboxy Carnosine HCl safe in cosmetics?
Decarboxy Carnosine HCl has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Decarboxy Carnosine HCl
Also known as: UNII-6X7K9I5QR7, beta-Alanylhistamine dihydrochloride, Carcinine dihydrochloride, Propanamide, 3-amino-N-(2-(1H-imidazol-4-yl)ethyl)-, dihydrochloride, Propanamide, 3-amino-N-(2-(1H-imidazol-5-yl)ethyl)-, hydrochloride (1:2)
INCI: DECARBOXY CARNOSINE HCL
Decarboxy Carnosine HCl (CAS 57022-38-5) is a cosmetic cosmetic ingredient functioning as Antistatic, hair conditioning, skin conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 57022-38-5 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Decarboxy Carnosine HCl is classified GHS Danger (H315, H318, H335) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Antistatic, hair conditioning, skin conditioning
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
3-amino-N-[2-(1H-imidazol-5-yl)ethyl]propanamide;dihydrochloride
InChIKey
ZQTUNIWBUQUKAM-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no specific CFR restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Decarboxy Carnosine HCl.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-static agent
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Decarboxy Carnosine HCl.
Known Synonyms
UNII-6X7K9I5QR7
beta-Alanylhistamine dihydrochloride
Carcinine dihydrochloride
Propanamide, 3-amino-N-(2-(1H-imidazol-4-yl)ethyl)-, dihydrochloride
Propanamide, 3-amino-N-(2-(1H-imidazol-5-yl)ethyl)-, hydrochloride (1:2)
Chemical Function
Anti-static agent
Softener and conditioner
Australian Status
AICIS status: listed_with_terms
Assessment: This chemical has been assessed as a component of dermal cosmetic products at concentrations no more than 0.05%. This chemical is not to be used in topical products intended for the eye.
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
CARCININE DIHYDROCHLORIDE
ChEMBL ID
CHEMBL1255583
Frequently Asked Questions
Is Decarboxy Carnosine HCl allowed in the EU?
Decarboxy Carnosine HCl EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Decarboxy Carnosine HCl do in cosmetics?
Decarboxy Carnosine HCl functions as: Antistatic, hair conditioning, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 57022-38-5.
Is Decarboxy Carnosine HCl used outside cosmetics?
Decarboxy Carnosine HCl also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Decarboxy Carnosine HCl have different safety status in cosmetics vs industrial chemicals?
Decarboxy Carnosine HCl is classified GHS Danger (H315, H318, H335) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Decarboxy Carnosine HCl compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
1-Methylhydantoin-2-imide (Creatinine)
Excellent
Same category
Skin conditioning (skin brightening/l...
4-Amino-3-Hydroxybutyric Acid
Excellent
Same category
Skin Conditioning
Acetyl Glycyl Beta-Alanine
Excellent
Same category
Skin conditioning agent with melanin ...
Acetyl Tripeptide-1
Excellent
Same category
Skin Conditioning
Acetylneuraminic Acid
Excellent
Same category
Skin Conditioning, Skin Protecting
Acetylphytosphingosine
Excellent
Same category
Skin Conditioning, Hair Conditioning;...
(20S)-Protopanaxadiol
Moderate
Similar safety
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
Moderate
Similar safety
Antimicrobial, antioxidant, humectant
(Licorice/Reynoutria Japonica) Root/Stem Extract
Moderate
Similar safety
Skin conditioning, antioxidant
(SH-Pentapeptide-10 6-Aminocaprooyl SH-Pentapeptide-11) SP
Moderate
Similar safety
Skin/hair conditioning (peptide-based...
1,2,3,4,4a,5,6,7-Octahydro-2,5,5-Trimethyl-2-Naphthol
Moderate
Similar safety
Fragrance ingredient
1,2,3,4,4a,7,8,8a-Octahydro-2,4a,5,8a-Tetramethyl-Naphthyl Formate
Moderate
Similar safety
Fragrance ingredient
DECAHYDRO-4,8,8-TRIMETHYL-9-METHYLENE-1,4-METHANOAZULENE/FORMIC ACID/BORON TRIFLUORIDE
Good
Browse nearby
Perfuming
DECAHYDRO-ISOPROPYL-DIMETHYL-PHENANTHRENE-1-METHANOL ACETATE
Good
Browse nearby
Perfuming
DECAPEPTIDE-1
Good
Browse nearby
Skin Conditioning
Is Decarboxy Carnosine HCl in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Decarboxy Carnosine HCl in your formulation.