Good Cosmetic Ingredient NOAEL Data GHS Classified

DIETHYL PHTHALATE

CAS Number
84-66-2
Function
Denaturant, Film Forming, Fragrance, Hair Conditioning, Plasticiser, Solvent
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status Permitted
🇺🇸 US Status permitted
US Notes CIR: S - JACT 4(3):267-303, 1985; IJT 24(Suppl. 1):1-102, 2005; IJT 36(Suppl 2):14-58, 2017

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

5 study endpoints found for DIETHYL PHTHALATE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 150 mg/kg bw/day oral rat oral REACH
NOAEL 12.5 other dermal code:3543 dermal REACH
NOAEL 0.1 other oral rat oral REACH
NOAEL 75 other dermal rat dermal REACH
LOAEL 2 other other dog oral REACH

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Routes of Exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

Expert Verdict

DIETHYL PHTHALATE is listed in the EU CosIng database with functions: Denaturant, Film Forming, Fragrance, Hair Conditioning, Plasticiser, Solvent It is permitted in the EU without specific restrictions.

⚠️
Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted hair-conditioning fragrance needs-enrichment endocrine_disruptor ifra_fragrance

Frequently Asked Questions

Is DIETHYL PHTHALATE safe in cosmetics?

DIETHYL PHTHALATE is listed in the EU CosIng database with functions: Denaturant, Film Forming, Fragrance, Hair Conditioning, Plasticiser, Solvent It is permitted in the EU without specific restrictions. The EU classifies DIETHYL PHTHALATE as "Permitted". Safety rating: GOOD. 5 toxicological study endpoint(s) are available in our database.

Is DIETHYL PHTHALATE allowed in the EU?

DIETHYL PHTHALATE EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does DIETHYL PHTHALATE do in cosmetics?

DIETHYL PHTHALATE functions as: Denaturant, Film Forming, Fragrance, Hair Conditioning, Plasticiser, Solvent. It is classified as a cosmetic ingredient in our database. CAS number: 84-66-2.

What is the NOAEL for DIETHYL PHTHALATE?

The NOAEL (No Observed Adverse Effect Level) for DIETHYL PHTHALATE is 150 mg/kg bw/day based on a oral study via oral route in rat. A total of 5 study endpoints are available. Source: REACH.

Compliance Tools

Check DIETHYL PHTHALATE compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
 🧮
MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

Related Ingredients

NONAN-3-ONE
Good
IRIS FLORENTINA ROOT
Good
ALOE BARBADENSIS LEAF
Good
METHYLCYCLOPENTENOLONE
Good
P-MENTHEN-6-YL-PROPANONE
Good
Browse all 30,000+ ingredients →
📱

Is DIETHYL PHTHALATE in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for DIETHYL PHTHALATE in your formulation.

Ingredient Decoder MoS Calculator