Regulatory Status
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Safety Data
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Expert Verdict
Cytotoxicity to HDF cells above 0.625 µM and DPC cells above 0.39 µM; pharmacological activity as antimalarial drug precursor creates regulatory boundary risk; China explicitly prohibits drug ingredients in cosmetics; formulation stability challenges warrant caution.
Frequently Asked Questions
Is Dihydroartemisinic Acid safe in cosmetics?
Cytotoxicity to HDF cells above 0.625 µM and DPC cells above 0.39 µM; pharmacological activity as antimalarial drug precursor creates regulatory boundary risk; China explicitly prohibits drug ingredients in cosmetics; formulation stability challenges warrant caution. The EU classifies Dihydroartemisinic Acid as "permitted". Safety rating: MODERATE.
Is Dihydroartemisinic Acid allowed in the EU?
Dihydroartemisinic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dihydroartemisinic Acid do in cosmetics?
Dihydroartemisinic Acid functions as: Skin conditioning (experimental) — anti-aging, whitening, antibacterial, anti-glycation activities demonstrated in vitro. It is classified as a cosmetic ingredient in our database. CAS number: 85031-59-0.
What is the Margin of Safety for Dihydroartemisinic Acid?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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