Diisobutyl Sodium Sulfosuccinate
INCI: DIISOBUTYL SODIUM SULFOSUCCINATE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Diisobutyl Sodium Sulfosuccinate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 750 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 750 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 750 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >30 mg/kg bw/day | other | dog | oral | REACH |
| NOAEL | 750 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 750 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >30 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 125 mg/kg bw/day | oral | monkey | oral | REACH |
| NOAEL | 250 mg/kg bw/day | oral | dog | oral | REACH |
Expert Verdict
Potential skin degreasing at high concentrations; standard anionic surfactant precautions apply; supplied as approximately 45% aqueous solution
Frequently Asked Questions
Is Diisobutyl Sodium Sulfosuccinate safe in cosmetics?
Potential skin degreasing at high concentrations; standard anionic surfactant precautions apply; supplied as approximately 45% aqueous solution The EU classifies Diisobutyl Sodium Sulfosuccinate as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.
Is Diisobutyl Sodium Sulfosuccinate allowed in the EU?
Diisobutyl Sodium Sulfosuccinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Diisobutyl Sodium Sulfosuccinate do in cosmetics?
Diisobutyl Sodium Sulfosuccinate functions as: Surfactant, wetting agent, foam booster, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 127-39-9.
What is the Margin of Safety for Diisobutyl Sodium Sulfosuccinate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Diisobutyl Sodium Sulfosuccinate?
The NOAEL (No Observed Adverse Effect Level) for Diisobutyl Sodium Sulfosuccinate is 750 mg/kg bw/day based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.
Compliance Tools
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