Diisononyl Adipate
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
5 study endpoints found for Diisononyl Adipate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 12000 ppm | oral | rat | oral | REACH |
| NOAEL | 200 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 200 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 6300 ppm | oral | rat | oral | REACH |
| NOAEL | 1600 ppm | oral | mouse | oral | REACH |
Expert Verdict
Frequently Asked Questions
Is Diisononyl Adipate safe in cosmetics?
Diisononyl Adipate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 5 toxicological study endpoint(s) are available in our database.
Is Diisononyl Adipate allowed in the EU?
Diisononyl Adipate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Diisononyl Adipate do in cosmetics?
Diisononyl Adipate functions as: Plasticizer; Softener and conditioner; Solvent. It is classified as a cosmetic ingredient in our database. CAS number: 33703-08-1.
What is the Margin of Safety for Diisononyl Adipate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Diisononyl Adipate?
The NOAEL (No Observed Adverse Effect Level) for Diisononyl Adipate is 12000 ppm based on a oral study via oral route in rat. A total of 5 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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