Dimethicone/Polyglycerin-3 Crosspolymer

INCI: DIMETHICONE/POLYGLYCERIN-3 CROSSPOLYMER

CAS Number
Not individually assigned
Function
Skin conditioning agent with emollient and emulsifying properties
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted. CIR-reviewed (2012): concluded safe as used

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Excellent safety profile with strong direct safety dataset. Not mutagenic (Ames negative at 5000 µg/plate), not irritating (rabbit PPI 1.30). Product mixtures contain <20 ppm heavy metals and <2 ppm arsenic with no PEG-related contaminant concerns. Polyglycerin-3 component is well-characterized and non-toxic.

⚠️
Concern Level: Low

Frequently Asked Questions

Is Dimethicone/Polyglycerin-3 Crosspolymer safe in cosmetics?

Excellent safety profile with strong direct safety dataset. Not mutagenic (Ames negative at 5000 µg/plate), not irritating (rabbit PPI 1.30). Product mixtures contain <20 ppm heavy metals and <2 ppm arsenic with no PEG-related contaminant concerns. Polyglycerin-3 component is well-characterized and non-toxic. The EU classifies Dimethicone/Polyglycerin-3 Crosspolymer as "permitted". Safety rating: EXCELLENT.

Is Dimethicone/Polyglycerin-3 Crosspolymer allowed in the EU?

Dimethicone/Polyglycerin-3 Crosspolymer EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dimethicone/Polyglycerin-3 Crosspolymer do in cosmetics?

Dimethicone/Polyglycerin-3 Crosspolymer functions as: Skin conditioning agent with emollient and emulsifying properties. It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned.

What is the Margin of Safety for Dimethicone/Polyglycerin-3 Crosspolymer?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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