Dimethiconol/IPDI Copolymer

INCI: DIMETHICONOL/IPDI COPOLYMER

CAS Number
193281-67-3
Function
Not reported to VCRP; no recorded uses at time of CIR review
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted by omission โ€” not listed in 21 CFR 700.11โ€“700.35; no VCRP uses reported

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Explicitly excluded from CIR safe as used conclusion. IPDI is a known respiratory sensitizer with occupational asthma risk and dermal sensitizer properties. No commercial cosmetic uses reported. Requires standalone safety assessment with specific residual monomer and isocyanate testing before any cosmetic use.

โš ๏ธ
Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Dimethiconol/IPDI Copolymer safe in cosmetics?

Explicitly excluded from CIR safe as used conclusion. IPDI is a known respiratory sensitizer with occupational asthma risk and dermal sensitizer properties. No commercial cosmetic uses reported. Requires standalone safety assessment with specific residual monomer and isocyanate testing before any cosmetic use. The EU classifies Dimethiconol/IPDI Copolymer as "prohibited". Safety rating: POOR.

Is Dimethiconol/IPDI Copolymer allowed in the EU?

Dimethiconol/IPDI Copolymer EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Dimethiconol/IPDI Copolymer do in cosmetics?

Dimethiconol/IPDI Copolymer functions as: Not reported to VCRP; no recorded uses at time of CIR review. It is classified as a cosmetic ingredient in our database. CAS number: 193281-67-3.

What is the Margin of Safety for Dimethiconol/IPDI Copolymer?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Dimethiconol/IPDI Copolymer in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Dimethiconol/IPDI Copolymer in your formulation.