Graphene Oxide

INCI: GRAPHENE OXIDE

CAS Number
2640657-49-2
Function
Not well-established in cosmetics; CosIng-listed with no assigned cosmetic function
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific cosmetic prohibition; general FDCA safety requirements apply; no CIR review

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Nanomaterial with toxicity highly dependent on particle size, surface structure, functionalization, charge, and impurities; requires mandatory SCCS opinion in EU; potential pulmonary toxicity via inhalation; limited OECD test data for specific commercial grades only; no cosmetic-specific systemic toxicity, NOAEL, or dermal penetration data available.

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Concern Level: High

Frequently Asked Questions

Is Graphene Oxide safe in cosmetics?

Nanomaterial with toxicity highly dependent on particle size, surface structure, functionalization, charge, and impurities; requires mandatory SCCS opinion in EU; potential pulmonary toxicity via inhalation; limited OECD test data for specific commercial grades only; no cosmetic-specific systemic toxicity, NOAEL, or dermal penetration data available. The EU classifies Graphene Oxide as "permitted". Safety rating: POOR.

Is Graphene Oxide allowed in the EU?

Graphene Oxide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Graphene Oxide do in cosmetics?

Graphene Oxide functions as: Not well-established in cosmetics; CosIng-listed with no assigned cosmetic function. It is classified as a cosmetic ingredient in our database. CAS number: 2640657-49-2.

What is the Margin of Safety for Graphene Oxide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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