Dimethylaminopropyl Methacrylamide (DMAPMA)
INCI: DIMETHYLAMINOPROPYL METHACRYLAMIDE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Dimethylaminopropyl Methacrylamide (DMAPMA). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 300 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 200 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
DMAPMA is a DMAPA analog; DMAPA is a well-documented contact allergen in cosmetics with sensitization concerns flagged by CIR Panel at concentrations ≥0.01%; free monomer must not be present in finished product; Certificate of Analysis required with residual DMAPMA quantification <10 ppm; not suitable for direct use in formulations.
Regulatory Flags
Frequently Asked Questions
Is Dimethylaminopropyl Methacrylamide (DMAPMA) safe in cosmetics?
DMAPMA is a DMAPA analog; DMAPA is a well-documented contact allergen in cosmetics with sensitization concerns flagged by CIR Panel at concentrations ≥0.01%; free monomer must not be present in finished product; Certificate of Analysis required with residual DMAPMA quantification <10 ppm; not suitable for direct use in formulations. The EU classifies Dimethylaminopropyl Methacrylamide (DMAPMA) as "permitted". Safety rating: POOR. 2 toxicological study endpoint(s) are available in our database.
Is Dimethylaminopropyl Methacrylamide (DMAPMA) allowed in the EU?
Dimethylaminopropyl Methacrylamide (DMAPMA) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dimethylaminopropyl Methacrylamide (DMAPMA) do in cosmetics?
Dimethylaminopropyl Methacrylamide (DMAPMA) functions as: Monomer for cationic polymer synthesis in hair care and skin care polymers. It is classified as a cosmetic ingredient in our database. CAS number: 5205-93-6.
What is the Margin of Safety for Dimethylaminopropyl Methacrylamide (DMAPMA)?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Dimethylaminopropyl Methacrylamide (DMAPMA)?
The NOAEL (No Observed Adverse Effect Level) for Dimethylaminopropyl Methacrylamide (DMAPMA) is 300 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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