Is Dimethylaminopropyl Methacrylamide (DMAPMA) safe in cosmetics?
Dimethylaminopropyl Methacrylamide (DMAPMA) has a safety rating of "POOR" in our database. EU status: permitted. US status: permitted.
Poor
Cosmetic Ingredient
Dimethylaminopropyl Methacrylamide (DMAPMA)
Also known as: 2-Propenamide, N-(3-(dimethylamino)propyl)-2-methyl-, N-[3-(Dimethylamino)propyl]methacrylamide, 2-Propenamide, N-[3-(dimethylamino)propyl]-2-methyl-, EINECS 226-002-3, UNII-63OBQ7BZDS
INCI: DIMETHYLAMINOPROPYL METHACRYLAMIDE
Dimethylaminopropyl Methacrylamide (DMAPMA) (CAS 5205-93-6) is a cosmetic cosmetic ingredient functioning as Monomer for cationic polymer synthesis in hair care and skin care polymers. NOAEL 200 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 5205-93-6 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Dimethylaminopropyl Methacrylamide (DMAPMA) is classified GHS Danger (H315, H317, H318) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Monomer for cationic polymer synthesis in hair care and skin care polymers
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
N-[3-(dimethylamino)propyl]-2-methylprop-2-enamide
InChIKey
GDFCSMCGLZFNFY-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
DMA-Benzamidopropyl/Methyl Polysilsesquioxane
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Dimethylaminopropyl Methacrylamide (DMAPMA).
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Dimethylaminopropyl Methacrylamide (DMAPMA) across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
No specific technical function
Expert Verdict
Expert safety assessment and concern-level summary for Dimethylaminopropyl Methacrylamide (DMAPMA).
Regulatory Flags
potential-allergen
Known Synonyms
2-Propenamide, N-(3-(dimethylamino)propyl)-2-methyl-
N-[3-(Dimethylamino)propyl]methacrylamide
2-Propenamide, N-[3-(dimethylamino)propyl]-2-methyl-
EINECS 226-002-3
UNII-63OBQ7BZDS
Chemical Function
No specific technical function
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Dimethylaminopropyl Methacrylamide (DMAPMA) allowed in the EU?
Dimethylaminopropyl Methacrylamide (DMAPMA) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dimethylaminopropyl Methacrylamide (DMAPMA) do in cosmetics?
Dimethylaminopropyl Methacrylamide (DMAPMA) functions as: Monomer for cationic polymer synthesis in hair care and skin care polymers. It is classified as a cosmetic ingredient in our database. CAS number: 5205-93-6.
Is Dimethylaminopropyl Methacrylamide (DMAPMA) used outside cosmetics?
Dimethylaminopropyl Methacrylamide (DMAPMA) also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Dimethylaminopropyl Methacrylamide (DMAPMA) have different safety status in cosmetics vs industrial chemicals?
Dimethylaminopropyl Methacrylamide (DMAPMA) is classified GHS Danger (H315, H317, H318) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Dimethylaminopropyl Methacrylamide (DMAPMA) compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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DIMETHYLAMINOPROPYL METHACRYLAMIDE
Moderate
Chemical family
Not Reported
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Good
Chemical family
Antioxidant
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Chemical family
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