Dimethylpiperazinium Aminopyrazolopyridine HCl

INCI: DIMETHYLPIPERAZINIUM AMINOPYRAZOLOPYRIDINE HCL

CAS Number
Not publicly assigned standard CAS; identified as A164 in SCCS dossier
Function
Oxidative hair dye precursor (developer/coupler)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
EU Max Conc. 2%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted under coal-tar hair dye exemption under FD&C Act ยง601(a); must carry caution labeling per 21 CFR 740.17

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Restricted to oxidative hair dye use only; not permitted for other cosmetic product types. Must not be used with nitrosating agents due to nitrosamine formation risk. Patch test advisable per industry standard. SCCS opinion required additional mutagenicity data before final positive conclusion; verify current Annex III entry status against latest Commission updates.

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Concern Level: Moderate

Frequently Asked Questions

Is Dimethylpiperazinium Aminopyrazolopyridine HCl safe in cosmetics?

Restricted to oxidative hair dye use only; not permitted for other cosmetic product types. Must not be used with nitrosating agents due to nitrosamine formation risk. Patch test advisable per industry standard. SCCS opinion required additional mutagenicity data before final positive conclusion; verify current Annex III entry status against latest Commission updates. The EU classifies Dimethylpiperazinium Aminopyrazolopyridine HCl as "restricted". Safety rating: GOOD.

Is Dimethylpiperazinium Aminopyrazolopyridine HCl allowed in the EU?

Dimethylpiperazinium Aminopyrazolopyridine HCl EU regulatory status: restricted. Maximum allowed concentration: 2%. This is based on EU Regulation 1223/2009 and its amendments.

What does Dimethylpiperazinium Aminopyrazolopyridine HCl do in cosmetics?

Dimethylpiperazinium Aminopyrazolopyridine HCl functions as: Oxidative hair dye precursor (developer/coupler). It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned standard CAS; identified as A164 in SCCS dossier.

What is the Margin of Safety for Dimethylpiperazinium Aminopyrazolopyridine HCl?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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