Diphenolic Acid

INCI: DIPHENOLIC ACID

CAS Number
126-00-1
Function
Chemical intermediate; structurally 4,4-bis(4-hydroxyphenyl)pentanoic acid (BPA analog)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not listed as a cosmetic ingredient in 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

BPA structural analog with potential endocrine disruption risk; GHS07 hazards include skin irritation (H315), eye irritation (H319), and respiratory irritation (H335); not recognized for cosmetic use and lacks CIR or SCCS review.

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Concern Level: High

Regulatory Flags

endocrine_disruptor

Frequently Asked Questions

Is Diphenolic Acid safe in cosmetics?

BPA structural analog with potential endocrine disruption risk; GHS07 hazards include skin irritation (H315), eye irritation (H319), and respiratory irritation (H335); not recognized for cosmetic use and lacks CIR or SCCS review. The EU classifies Diphenolic Acid as "permitted". Safety rating: POOR.

Is Diphenolic Acid allowed in the EU?

Diphenolic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Diphenolic Acid do in cosmetics?

Diphenolic Acid functions as: Chemical intermediate; structurally 4,4-bis(4-hydroxyphenyl)pentanoic acid (BPA analog). It is classified as a cosmetic ingredient in our database. CAS number: 126-00-1.

What is the Margin of Safety for Diphenolic Acid?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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