Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
6 study endpoints found for Dipotassium Oxalate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| LOAEL | 1900 mg/kg bw/day | oral | rat | oral | REACH |
| LOEL | 1980 mg/kg bw/day | oral | rat | oral | REACH |
| LOEL | 340 mg/kg bw/day | oral | mouse | oral | REACH |
| NOAEL | 162 mg/kg bw/day | oral | mouse | oral | REACH |
| LOEL | 0.03 other | oral | rat | oral | REACH |
| LOAEL | 1900 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
DO NOT USE IN COSMETICS. EU-prohibited due to systemic toxicity via ingestion/inhalation, mucosal burns, and renal damage from oxalate precipitation as calcium oxalate. GHS: H302+H312 (harmful if swallowed or in contact with skin).
Frequently Asked Questions
Is Dipotassium Oxalate safe in cosmetics?
DO NOT USE IN COSMETICS. EU-prohibited due to systemic toxicity via ingestion/inhalation, mucosal burns, and renal damage from oxalate precipitation as calcium oxalate. GHS: H302+H312 (harmful if swallowed or in contact with skin). The EU classifies Dipotassium Oxalate as "prohibited". Safety rating: POOR. 6 toxicological study endpoint(s) are available in our database.
Is Dipotassium Oxalate allowed in the EU?
Dipotassium Oxalate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Dipotassium Oxalate do in cosmetics?
Dipotassium Oxalate functions as: Chelating agent (industrial/analytical use; not a standard cosmetic ingredient). It is classified as a cosmetic ingredient in our database. CAS number: 583-52-8.
What is the Margin of Safety for Dipotassium Oxalate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Dipotassium Oxalate?
The NOAEL (No Observed Adverse Effect Level) for Dipotassium Oxalate is 1900 mg/kg bw/day based on a oral study via oral route in rat. A total of 6 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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