Moderate Cosmetic Ingredient NOAEL Data

Disperse Red 17

INCI: DISPERSE RED 17

CAS Number
3179-89-3
Function
Hair dyeing (azo dye); semi-permanent and oxidative formulations
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
EU Max Conc. 0.2%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically listed under 21 CFR 73/74/82; coal tar hair dye exemption applies with caution labeling

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Disperse Red 17. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
LOAEL 10 mg/kg bw/day oral rat Subchronic COSMOS_DB

Expert Verdict

Nitrosamine content must be less than 50 ppb; must not be used with nitrosating agents; the commercial product is approximately 40% active dye with dispersing agents that require separate toxicological consideration

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Concern Level: High

Regulatory Flags

eu_cosing_listed

Frequently Asked Questions

Is Disperse Red 17 safe in cosmetics?

Nitrosamine content must be less than 50 ppb; must not be used with nitrosating agents; the commercial product is approximately 40% active dye with dispersing agents that require separate toxicological consideration The EU classifies Disperse Red 17 as "prohibited". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.

Is Disperse Red 17 allowed in the EU?

Disperse Red 17 EU regulatory status: prohibited. Maximum allowed concentration: 0.2%. This is based on EU Regulation 1223/2009 and its amendments.

What does Disperse Red 17 do in cosmetics?

Disperse Red 17 functions as: Hair dyeing (azo dye); semi-permanent and oxidative formulations. It is classified as a cosmetic ingredient in our database. CAS number: 3179-89-3.

What is the Margin of Safety for Disperse Red 17?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Disperse Red 17?

The NOAEL (No Observed Adverse Effect Level) for Disperse Red 17 is 10 mg/kg bw/day based on a Subchronic study via oral route in rat. Source: COSMOS_DB.

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