Elephantopus Mollis Leaf Extract
INCI: ELEPHANTOPUS MOLLIS LEAF EXTRACT
Regulatory Status
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Safety Data
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Expert Verdict
Contains sesquiterpene lactones (molephantinin and analogs) with demonstrated cytotoxicity against multiple cell lines (IC50 27โ37 ฮผg/mL). While cytotoxicity data is from in-vitro cancer studies, it signals biologically active compounds that require dermal safety qualification. Asteraceae family is a known sensitizer group. Full toxicological dossier needed including genotoxicity screening.
Regulatory Flags
Frequently Asked Questions
Is Elephantopus Mollis Leaf Extract safe in cosmetics?
Contains sesquiterpene lactones (molephantinin and analogs) with demonstrated cytotoxicity against multiple cell lines (IC50 27โ37 ฮผg/mL). While cytotoxicity data is from in-vitro cancer studies, it signals biologically active compounds that require dermal safety qualification. Asteraceae family is a known sensitizer group. Full toxicological dossier needed including genotoxicity screening. The EU classifies Elephantopus Mollis Leaf Extract as "permitted". Safety rating: MODERATE.
Is Elephantopus Mollis Leaf Extract allowed in the EU?
Elephantopus Mollis Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Elephantopus Mollis Leaf Extract do in cosmetics?
Elephantopus Mollis Leaf Extract functions as: Skin conditioning (traditional use: ulcers, eczema, skin diseases). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.
What is the Margin of Safety for Elephantopus Mollis Leaf Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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