Epoxidized Soybean Oil

INCI: EPOXIDIZED SOYBEAN OIL

CAS Number
8013-07-8 [^1_13][^1_14]
Function
Emollient, skin conditioning, plasticizer
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” FDA GRAS for indirect food contact (21 CFR 181.27); not prohibited/restricted in cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Epoxidized soybean oil is permitted with good safety profile; epoxidation process denatures allergenic proteins; mild transient irritation may occur at high concentrations with no carcinogenic, genotoxic, or reproductive/developmental toxicity.

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Concern Level: Low

Regulatory Flags

plant-oil potential-allergen

Frequently Asked Questions

Is Epoxidized Soybean Oil safe in cosmetics?

Epoxidized soybean oil is permitted with good safety profile; epoxidation process denatures allergenic proteins; mild transient irritation may occur at high concentrations with no carcinogenic, genotoxic, or reproductive/developmental toxicity. The EU classifies Epoxidized Soybean Oil as "permitted". Safety rating: GOOD.

Is Epoxidized Soybean Oil allowed in the EU?

Epoxidized Soybean Oil EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Epoxidized Soybean Oil do in cosmetics?

Epoxidized Soybean Oil functions as: Emollient, skin conditioning, plasticizer. It is classified as a cosmetic ingredient in our database. CAS number: 8013-07-8 [^1_13][^1_14].

What is the Margin of Safety for Epoxidized Soybean Oil?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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