Epoxycyclododecane

INCI: EPOXYCYCLODODECANE

CAS Number
286-99-7 [^1_4]
Function
Fragrance agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific prohibition under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Epoxide functional group is reactive with mutagenicity concerns; limited IFRA/RIFM safety dossier publicly available; QSAR alerts for genotoxicity in cyclic epoxides; requires Ames test and dermal sensitization data for full CPSR.

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Concern Level: High

Regulatory Flags

potential-allergen fragrance-component

Frequently Asked Questions

Is Epoxycyclododecane safe in cosmetics?

Epoxide functional group is reactive with mutagenicity concerns; limited IFRA/RIFM safety dossier publicly available; QSAR alerts for genotoxicity in cyclic epoxides; requires Ames test and dermal sensitization data for full CPSR. The EU classifies Epoxycyclododecane as "permitted". Safety rating: MODERATE.

Is Epoxycyclododecane allowed in the EU?

Epoxycyclododecane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Epoxycyclododecane do in cosmetics?

Epoxycyclododecane functions as: Fragrance agent. It is classified as a cosmetic ingredient in our database. CAS number: 286-99-7 [^1_4].

What is the Margin of Safety for Epoxycyclododecane?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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